Physical properties of mephedrone | mephedrone sale london

The base is a yellowish liquid at ambient temperature. Mephedrone hydrochloride salt is a white or lightly colour powder. buy mephedrone UK

Thirdly, 4-Methylmethcathinone (also know as 4-MMC, M-CAT, drone, meow meow, and mephe drone) is a entactogen-stimulant substance of the cathinone class.

belongs to a group known as the substitute cathinone, which are derivatives of the active ingredient in the khat plant (Catha edulluis).

Mean while, Mephe drone was first synthesize in 1929, but did not become widely know until it was rediscover in 2003. By 2007, it was report to be available for sale on the internet. Also, by 2008 law enforcement agencies  become aware of the compound. Furthermore, by 2010 it had been report in most of Europe, becoming particularly prevalent in the United Kingdom.

Again, comes in the form of tablets or a powder, which users can swallow, snort, inject or insert rectally. It produces effects which are somewhat similar to those of MDMA, amphetamine, and cocaine. In addition, It is report to produce a mixture of classic stimulant and entactogenic effects effects reminiscent of cocaine and MDMA.

Pharmacology of Mephedrone |  mephedrone for sale online

Given its chemical structure, mephedrone is likely to act as a releasing agent and a reuptake inhibitor for monoamine neurotransmitters.

Such monoamine neurotransmitters are dopamine, serotonin and noradrenaline. buy mephedrone

Several articles published near the end of 2011 examined the effects of mephedrone in the brains of rats. Dopamine and serotonin were collected using microdialysis, and increases in dopamine and serotonin were measure.

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Mephe drone administration caused about a 500% increase in dopamine, and about a 950% increase in serotonin.

They reached their peak concentrations at 40 minutes and 20 minutes and return to baseline by 120 minutes after injection.

Analysis of the ratio for dopamine and serotonin indicate mephedrone was preferentially a serotonin releaser.

In Addition, half-lives for the decrease in dopamine and serotonin were found to have decay rates of 24.5 minutes and 25.5 minutes.